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The antiviral drug remdesivir does not reduce deaths among COVID-19 patients , as compare with standard care , according to the results of a magnanimous , international trial .
The Food and Drug Administration , in May , authorized remdesivir to be used in an emergency to treat COVID-19 , after a turgid clinical trial suggested that the drug reduces the time it takes for COVID-19 patient role to be discharged from the hospital , as compared with a placebo treatment , Live Science previously describe . As of August , the drug has been authorized for use in all patient role hospitalized with COVID-19 , not only those on supplemental atomic number 8 , The New York Times report . Thousands of U.S. patients have received the treatment , including the Chief Executive .
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About 4,100 of those patients served as a comparison group and received no drug treatments , while the rest received one of four drug , or a combining of several medications . These drug include remdesivir , hydroxychloroquine , an antiviral call lopinavir and an immune - perk up molecule called Interferon - β1a . About 650 patients received the interferon and lopinavir , together .
at long last , the survey results paint a picture that no single drug or drug combination significantly reduced death among patients , as equate with the no - drug grouping . In addition , the drugs did not reduce the luck that treat affected role would be placed on a ventilator , nor did the drug reduce patients ' clip in the hospital .
" The unpromising overall findings from the regimen test do to rebut early hopes " that the medications would reduce mortality among COVID-19 patients , the survey authors wrote . early trial already indicated that hydroxychloroquine and lopinavir do n’t concentrate deathrate , but the datum on remdesivir offers raw insight on whether the drug really work out , according to The Associated Press .
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" The big story is the determination that remdesivir produces no meaningful impact on natural selection , " Martin Landray , a professor of medication and epidemiology at Oxford University , say in a statement , consort to The Associated Press . However , Dr. Peter Chin - Hong , an infectious diseases expert at the University of California , San Francisco , told The New York Times that the trial final result might be somewhat skewed .
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The trial player were deal at 405 different hospitals around the world , each with their own treatment protocols , so factor beyond remdesivir may have impacted patient survival , he noted . In addition , remdesivir may still offer welfare to patients if givenearlyin the course of their illness , but that was n’t specifically addressed by the new study , Dr. Maricar Malinis , an infectious diseases physician at Yale University , told the Times .
But even if remdesivir helps some patient , it ’s still expensive and hard to lot , Landray say in a statement , consort to the AP . " This is a drug that has to be give by endovenous infusion for five to 10 days , " he said , note it cost about $ 2,550 per treatment course . ( The treatment line costs $ 3,120 for U.S. patient role with private indemnity , The Times describe . )
" COVID affects millions of multitude and their crime syndicate around the earth . We need scalable , affordable and just treatments , " Landray say .
Originally published on Live Science .
