Drew Barrymore, Natasha Lyonne and Aubrey Plaza in April 2023.Photo:Kevin Mazur/Getty

Drew Barrymore, Natasha Lyonne, Aubrey Plaza attend the 2023 TIME100 Gala at Jazz at Lincoln Center on April 26, 2023 in New York City.

Kevin Mazur/Getty

Drew Barrymorekeeps her talk show guests close — and her friends even closer!The Drew Barrymore Showhost — who celebrates her 50th birthday on Saturday, Feb. 22, 2025 — is known for her affectionate interviews, which have garnered mixed reception among viewers. During a chat withDax Shepardon the show in September 2024, she told the podcaster, “I get in trouble for physical proximity on this show.“She continued, “I guess a lot of people say ‘you’re too touchy’ about me. … I’m horrified when I hear that, and yet I can’t stop.”Although she toldEntertainment Tonightthat she would “try to practice physical distance,” she stipulated that she enjoys the company of others. As Barrymore celebrates a new milestone, see 22 photos of the iconic actress cozying up with her many celebrity friends, fromCameron DiazandLucy LiutoJimmy Fallon.

Drew Barrymorekeeps her talk show guests close — and her friends even closer!

The Drew Barrymore Showhost — who celebrates her 50th birthday on Saturday, Feb. 22, 2025 — is known for her affectionate interviews, which have garnered mixed reception among viewers. During a chat withDax Shepardon the show in September 2024, she told the podcaster, “I get in trouble for physical proximity on this show.”

She continued, “I guess a lot of people say ‘you’re too touchy’ about me. … I’m horrified when I hear that, and yet I can’t stop.”

Although she toldEntertainment Tonightthat she would “try to practice physical distance,” she stipulated that she enjoys the company of others. As Barrymore celebrates a new milestone, see 22 photos of the iconic actress cozying up with her many celebrity friends, fromCameron DiazandLucy LiutoJimmy Fallon.

01of 20Cameron Diaz and Lucy LiuCameron Diaz, Drew Barrymore and Lucy Liu in June 2003.Scott Gries/GettyHerCharlie’s Angelssquad Cameron Diaz and Lucy Liu have been showing Barrymore love for years!

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Cameron Diaz and Lucy Liu

Cameron Diaz, Drew Barrymore and Lucy Liu in June 2003.Scott Gries/Getty

(L-R) Actresses Cameron Diaz, Drew Barrymore and Lucy Liu appear on stage during MTV’s Total Request Live June 26, 2003 at the MTV Times Square Studios in New York City.

Scott Gries/Getty

HerCharlie’s Angelssquad Cameron Diaz and Lucy Liu have been showing Barrymore love for years!

02of 20

Courtney Love

American singer, songwriter, actress and musician Courtney Love, wearing a pink off-shoulder dress, is hugged from behind by American actress Drew Barrymore, wearing a black trouser suit, attend the 5th Annual Blockbuster Entertainment Awards, held at the Shrine Auditorium in Los Angeles, California, 25th May 1999.

Vinnie Zuffante/Getty

Barrymore andCourtney Loveare best friends to this day, and the talk show host is even the godmother of Love’s daughterFrances Bean.

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Jimmy Fallon

Jimmy Fallon and Drew Barrymore during ShoWest 2005 - 20th Century Fox Luncheon at Pairs Hotel in Las Vegas, Nevada, United States.

J.Sciulli/WireImage

Barrymore and Jimmy Fallon go way back, costarring in the 2005 rom-comFever Pitch.

04of 20

Steven Spielberg

Ke Huy Quan, Steven Spielberg and Drew Barrymore attend the 2023 TIME100 Gala at Jazz at Lincoln Center on April 26, 2023 in New York City.

Ke Huy Quanand Drew Barrymore gave Steven Spielberg — who directed them as child stars — a smooch on the cheek when they reunited at the 2023 TIME100 Gala.

05of 20

Natasha Lyonne and Aubrey Plaza

Natasha Lyonne, Aubrey Plaza and Drew Barrymore attend the 2023 TIME100 Gala at Jazz at Lincoln Center on April 26, 2023 in New York City.

Also at the TIME100 Gala, Barrymore joked around withNatasha LyonneandAubrey Plaza.

06of 20

Ali Wong

Ali Wong and Drew Barrymore attend the 2023 TIME100 Gala at Jazz at Lincoln Center on April 26, 2023 in New York City

She also met up with a glamorousAli Wongat the TIME100 Gala for a super smiley photo.

07of 20Adam SandlerDrew Barrymore and Adam Sandler in October 2022.Craig Barritt/GettyThree-time costars Barrymore andAdam Sandler’s working relationship dates back to 1998’sThe Wedding Singer.

07of 20

Adam Sandler

Drew Barrymore and Adam Sandler in October 2022.Craig Barritt/Getty

Drew Barrymore and Adam Sandler attend Netflix’s Hustle New York City SAG Screening at DGA Theater on October 26, 2022 in New York City

Craig Barritt/Getty

Three-time costars Barrymore andAdam Sandler’s working relationship dates back to 1998’sThe Wedding Singer.

08of 20

Jay-Z

Jay-Z (L) and Drew Barrymore attend the 36th Annual Rock & Roll Hall Of Fame Induction Ceremony at Rocket Mortgage Fieldhouse on October 30, 2021 in Cleveland, Ohio

At the 2021 Rock & Roll Hall of Fame Induction Ceremony, Barrymore beamed next to inducteeJay-Z.

09of 20

Cameron Diaz

Drew Barrymore and Cameron Diaz in May 2019.Tommaso Boddi/WireImage

Drew Barrymore and Cameron Diaz attend a ceremony honoring Lucy Liu With Star On The Hollywood Walk Of Fame on May 01, 2019 in Hollywood, California

Tommaso Boddi/WireImage

10of 20Sydney SweeneyDrew Barrymore and Sydney Sweeney in December 2023.The Hapa Blonde/GC ImagesAfter her appearance onThe Drew Barrymore Show,Sydney Sweeneyembraced the host on the streets of New York City…

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Sydney Sweeney

Drew Barrymore and Sydney Sweeney in December 2023.The Hapa Blonde/GC Images

Sydney Sweeney and Glen Powell are seen in Midtown on December 11, 2023 in New York City

The Hapa Blonde/GC Images

After her appearance onThe Drew Barrymore Show,Sydney Sweeneyembraced the host on the streets of New York City…

11of 20Glen PowellSydney Sweeney, Drew Barrymore and Glen Powell in December 2023.James Devaney/GC Images…and so did Sweeney’sAnyone but YoucostarGlen Powell!

11of 20

Glen Powell

Sydney Sweeney, Drew Barrymore and Glen Powell in December 2023.James Devaney/GC Images

Drew Barrymore, Sydney Sweeney and Glen Powell are seen in Rockefeller Center on December 11, 2023 in New York Cit

James Devaney/GC Images

…and so did Sweeney’sAnyone but YoucostarGlen Powell!

12of 20Toni ColletteDrew Barrymore and Toni Collette in September 2015.Mike Marsland/WireImageBarrymore andToni Collettewere not afraid to take loved-up photos during the press tour for their 2015 filmMiss You Already.

12of 20

Toni Collette

Drew Barrymore and Toni Collette in September 2015.Mike Marsland/WireImage

Drew Barrymore and Toni Collette attend the European Premiere of “Miss You Already” at Vue West End on September 17, 2015 in London, England

Mike Marsland/WireImage

Barrymore andToni Collettewere not afraid to take loved-up photos during the press tour for their 2015 filmMiss You Already.

13of 20

Hannah Waddingham

Hannah Waddingham and Drew Barrymore attend the Christian Siriano FW 2022 Runway Collection on February 12, 2022 in New York City.

Jamie McCarthy/Getty

Sitting front row at the Christian Siriano show during New York Fashion Week, Barrymore leaned in to take a selfie withHannah Waddingham.

14of 20Jessica LangeDrew Barrymore and Jessica Lange in April 2009.Jeffrey Mayer/WireImageBarrymore held tight toGrey GardenscostarJessica Langeat the film’s Los Angeles premiere in 2009.

14of 20

Jessica Lange

Drew Barrymore and Jessica Lange in April 2009.Jeffrey Mayer/WireImage

Actresses Drew Barrymore and Jessica Lange arrive at the Los Angeles premiere of “Grey Gardens” at Grauman’s Chinese Theater on April 16, 2009 in Hollywood, California.

Jeffrey Mayer/WireImage

Barrymore held tight toGrey GardenscostarJessica Langeat the film’s Los Angeles premiere in 2009.

15of 20Kristen WiigDrew Barrymore and Kristen Wiig in April 2009.PATRICK MCMULLAN/Patrick McMullan via GettyAt the afterparty forGrey Gardens, Barrymore looked like an Old Hollywood star as she got cheek-to-cheek withKristen Wiig.

15of 20

Kristen Wiig

Drew Barrymore and Kristen Wiig in April 2009.PATRICK MCMULLAN/Patrick McMullan via Getty

Drew Barrymore and Kristen Wiig attend HBO FILMS Presents the After party for New York Premiere of GREY GARDENS at The Pierre Hotel on April 14, 2009 in New York City.

PATRICK MCMULLAN/Patrick McMullan via Getty

At the afterparty forGrey Gardens, Barrymore looked like an Old Hollywood star as she got cheek-to-cheek withKristen Wiig.

16of 20Timothy OlyphantDrew Barrymore and Timothy Olyphant in February 2017.Jason LaVeris/FilmMagicBarrymore looked lovingly at herSanta Clarita Dietco-leadTimothy Olyphantat the series premiere in 2017.

16of 20

Timothy Olyphant

Drew Barrymore and Timothy Olyphant in February 2017.Jason LaVeris/FilmMagic

Actor Timothy Olyphant and actress Drew Barrymore attend the premiere of “Santa Clarita Diet” at ArcLight Cinemas Cinerama Dome on February 1, 2017 in Hollywood, California.

Jason LaVeris/FilmMagic

Barrymore looked lovingly at herSanta Clarita Dietco-leadTimothy Olyphantat the series premiere in 2017.

17of 20

Liv Hewson

Liv Hewson and Drew Barrymore attend Netflix’s “Santa Clarita Diet” Season 2 Premiere at The Dome at Arclight Hollywood on March 22, 2018 in Hollywood, California.

Christopher Polk/Getty

She was also close to her other castmates on the Netflix horror sitcom, likeLiv Hewson.

18of 20Ben PlattDrew Barrymore and Ben Platt in May 2017.Bruce Glikas/Bruce Glikas/FilmMagicShe supportedBen Plattbackstage at the Broadway production ofDear Evan Hansen.

18of 20

Ben Platt

Drew Barrymore and Ben Platt in May 2017.Bruce Glikas/Bruce Glikas/FilmMagic

Drew Barrymore and Ben Platt pose backstage at the hit musical “Dear Evan Hansen” on Broadway at The Music Box Theater on May 17, 2017 in New York City

Bruce Glikas/Bruce Glikas/FilmMagic

She supportedBen Plattbackstage at the Broadway production ofDear Evan Hansen.

19of 20

Ross Mathews

Ross Mathews and Drew Barrymore are seen on the set of “The Drew Barrymore Show” on May 14, 2024 in New York City

Jason Howard/Bauer-Griffin/GC Images

It’s no surprise that she’s so close — literally — with herDrew Barrymore Showco-hostRoss Mathews.

20of 20Nate BurlesonDrew Barrymore and Nate Burleson in September 2024.Steven Ferdman/GettyBarrymore was ecstatic when herHollywood Squaresco-hostNate Burlesonshowed up to her Paley Museum event in September 2024.

20of 20

Nate Burleson

Drew Barrymore and Nate Burleson in September 2024.Steven Ferdman/Getty

Drew Barrymore and Nate Burleson attend Daytime At Night: An Evening With The Drew Barrymore Show at The Paley Museum on September 09, 2024 in New York City.

Steven Ferdman/Getty

Barrymore was ecstatic when herHollywood Squaresco-hostNate Burlesonshowed up to her Paley Museum event in September 2024.

source: people.com